ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,658, issued on April 14, was assigned to Oregon Health & Science University (Portland, Ore.).

"Hepatitis B virus-specific T cell responses" was invented by Klaus J. Fruh (Portland, Ore.), Louis J. Picker (Portland, Ore.), Benjamin J. Burwitz (Portland, Ore.), Scott G. Hansen (Portland, Ore.) and Jonah B. Sacha (Beaverton, Ore.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods to generate an immune response for the treatment or prevention of hepatitis B virus infection. This disclosure also relates to methods to generate MHC-E and/or MHC-II restricted CD8+ T cells for the treatment or prevention of hepatitis B ...