ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,714,693, issued on Aug. 25, was assigned to Ophirex Inc. (Corte Madera, Calif.).
"Use of SPLA2 inhibitors to treat envenomation by snakes and wasps" was invented by Matthew R. Lewin (Corte Madera, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides medicaments and methods for treating envenomation using small molecule inhibitors of secretory phospholipase A2 (sPLA2). The sPLA2 inhibitor AZD2716 and related compounds can be used as monotherapy. Alternatively, the sPLA2 inhibitor varespladib and/or methyl varespladib can be used in combination with a statin. When a subject has been envenomed (for example, by a snake bite or bee ...