US Patent Issued to Novartis on Sept. 15 for "Immunoglobulin variants" (French, American, Swiss Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,502, issued on Sept. 15, was assigned to Novartis AG (Basel, Switzerland).

"Immunoglobulin variants" was invented by John Blankenship (Acton, Mass.), Justine Celine Patricia Guyot (Zimmersheim, France), Brian Holmberg (Somerville, Mass.), Sebastien Irigaray (Zimmersheim, France) and Darko Skegro (Riehen, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an Fc variant of a parent IgA Fc polypeptide, wherein the Fc variant exhibits altered binding to FcAlphaRs, wherein the Fc variant comprises at least one amino acid modification in the Fc region of the parent Fc polypeptide."

The patent was filed on April 29,...