ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,189, issued on Sept. 15, was assigned to Northwestern University (Evanston, Ill.).

"Methods for enhancing cytotoxic cancer therapy through modulation of purine biosynthesis pathways" was invented by Atique U. Ahmed (Evanston, Ill.), Jack M. Shireman (Chicago) and Cheol H. Park (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods and compositions for treating proliferative cell diseases and disorders such as cancers. Particularly disclosed are methods and composition for treating cancers such as glioblastoma by administering a therapeutic agent that alters the pathways used for purine biosynthesis by inhibiting the biologica...