US Patent Issued to Northwestern University on March 3 for "HECT E3 ubiquitin liagase inhibitors and uses thereof" (Illinois Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,588, issued on March 3, was assigned to Northwestern University (Evanston, Ill.).

"HECT E3 ubiquitin liagase inhibitors and uses thereof" was invented by Hiroaki Kiyokawa (Evanston, Ill.), Rama K. Mishra (Evanston, Ill.) and Chi-Hao Luan (Evanston, Ill.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compounds, compositions, and methods for inhibiting HECT E3 ubiquitin ligases. In some embodiments, the compounds are formulated as a pharmaceutical composition and administered to a subject in need thereof. In some embodiments, the subject in need thereof is diagnosed with a neurological disease or a cancer characterized by increase...