US Patent Issued to Northwestern University on March 17 for "Methods for enhancing cytotoxic cancer therapy through inhibition of ATG4B" (Illinois Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,088, issued on March 17, was assigned to Northwestern University (Evanston, Ill.).

"Methods for enhancing cytotoxic cancer therapy through inhibition of ATG4B" was invented by Shi-Yuan Cheng (Glenview, Ill.), Bo Hu (Glenview, Ill.) and Tianzhi Huang (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods and compositions for treating cell proliferative diseases and disorders such as cancers. Particularly disclosed are methods and composition for treating cancers such as glioblastoma by administering a therapeutic agent that inhibits the biological activity of the autophagy related 4B cysteine peptidase (ATG4B) protein in conju...