US Patent Issued to Northwestern University on July 28 for "Small molecule modulators of sigma-1 and sigma-2 receptors and uses thereof" (Illinois Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,236, issued on July 28, was assigned to Northwestern University (Evanston, Ill.).

"Small molecule modulators of sigma-1 and sigma-2 receptors and uses thereof" was invented by Gary E. Schiltz (Naperville, Ill.), Iredia D. Iyamu (Evanston, Ill.), Rama K. Mishra (Chicago), Wei Lv (Evanston, Ill.) and Neha Malik (Evanston, Ill.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is in the field of medicinal chemistry. In particular, the invention relates to anew class of small-molecules having a tetrahydroindazole structure which function as modulators (e.g., activators or inhibitors) of sigma-1 and/or sigma-2 receptors, and their use as ther...