ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,557,999, issued on Feb. 24, was assigned to Northeastern University (Boston).
"Quantitative measurement of disruptions in the blood brain barrier" was invented by Craig Ferris (Holden, Mass.), Ju Qiao (Boston), Praveen Kulkarni (East Walpole, Mass.) and Codi Gharagouzloo (Carlisle, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods for determining blood brain barrier disruption in a subject in need thereof. The methods include administering intravascularly a contrast agent to the subject; performing quantitative ultra-short time-to-echo contrast-enhanced magnetic resonance imaging (QUTE-CE MRI) on a region of interest of the subjec...