ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,429, issued on April 14, was assigned to NORTH CAROLINA STATE UNIVERSITY (Raleigh, N.C.).

"Methods for controlling treatment volumes, thermal gradients, muscle stimulation, and immune responses in pulsed electric field treatments" was invented by Michael Benjamin Sano (Cary, N.C.), Christopher Fesmire (Raleigh, N.C.) and Ross A. Petrella (Richmond, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Pursuant to embodiments of the present invention, a method of performing electronically controlled electrotherapy may include modifying or killing target cells and simultaneously modifying a secondary outcome by delivering electrical pulses and dynamical...