US Patent Issued to NOF on April 7 for "Method for producing maleimide polyethylene glycol derivative" (Japanese Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,336, issued on April 7, was assigned to NOF Corp. (Tokyo).

"Method for producing maleimide polyethylene glycol derivative" was invented by Daiki Ozone (Taketoyo-cyo, Japan), Shota Mori (Ebina, Japan) and Masaki Ota (Taketoyo-cyo, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for producing a maleimide polyethylene glycol derivative, may including a reaction step of heating a maleimide polyethylene glycol derivative having a protective group, in a solvent in the presence of silica gel to cause deprotection. A maleimide polyethylene glycol derivative can be produced at a high maleimidization rate while restraining deterioration of a mal...