US Patent Issued to NIPPON MEDICAL SCHOOL FOUNDATION, TAKARA BIO on April 21 for "Method for producing nucleic acid-encapsulated AAV hollow particle" (Japanese Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,845, issued on April 21, was assigned to NIPPON MEDICAL SCHOOL FOUNDATION (Tokyo) and TAKARA BIO INC. (Shiga, Japan).

"Method for producing nucleic acid-encapsulated AAV hollow particle" was invented by Takashi Okada (Tokyo), Junichi Mineno (Kusatsu, Japan) and Hideto Chono (Kusatsu, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for producing a nucleic acid-encapsulated adeno-associated virus (AAV) hollow particle, comprising the following steps: (1) preparing a linear nucleic acid fragment comprising a sequence for A region and a sequence for D' region in an AAV inverted terminal repeat (ITR) (i.e., an AD sequence) or a sequence co...