ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,638, issued on Aug. 18, was assigned to NINGBO INNOVATIVE MECHANISM BIOSCIENCE LLC (Ningbo City, China).

"Protein heterodimer and use thereof" was invented by Jinyu Zhang (Chongqing, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides a protein heterodimer and use thereof. The protein heterodimer comprises a first polypeptide chain and a second polypeptide chain different from the first polypeptide chain, wherein the first polypeptide chain comprises IL12a, and the second polypeptide chain comprises interleukin-12b (IL12b). The protein heterodimer also comprises interleukin-2 (IL2) or its functional fragments, granu...