ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,131, issued on Sept. 8, was assigned to NICOX S.A. (Valbonne, France).

"Compositions for the treatment of glaucoma and ocular hypertension" was invented by Nicoletta Almirante (Milan), Stefania Brambilla (Merone, Italy), Francesco Impagnatiello (Milan), Elena Bastia (Milan) and Corinna Galli (Marcallo con Casone, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to ophthalmic compositions comprising a nitric oxide releasing phosphodiesterase type 5 inhibitor (NO-PDE5 inhibitor) and a prostaglandin analog, and to the use of these ophthalmic compositions for the treatment of all forms of glaucoma or ocular hypertension as well...