US Patent Issued to New England Biolabs on May 26 for "Fragmentation of DNA" (Massachusetts Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,712, issued on May 26, was assigned to New England Biolabs Inc. (Ipswich, Mass.).

"Fragmentation of DNA" was invented by Lynne Apone (Waltham, Mass.), Brittany S. Sexton (Amesbury, Mass.), Margaret Heider (Ipswich, Mass.), Louise Js Williams (Reading, Mass.) and Eileen T. Dimalanta (Wakefield, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a polymerase-free enzyme mix (FRAG) for fragmenting double-stranded DNA. In some embodiments the enzyme mix may comprise a double-stranded DNA nickase and at least one of a DNA ligase capable of sealing a nick within a DNA, and a single-strand specific DNA nuclease. Methods for fragmenting ...