ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,822, issued on March 3, was assigned to NDSU RESEARCH FOUNDATION (Fargo, N.D.).
"Device for manufacture of T-cells for autologous cell therapy" was invented by Dharmakeerthi Nawarathna (Fargo, N.D.), Logeeshan Velmanickam (Fargo, N.D.) and Vidura Jayasooriya (Fargo, N.D.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a device for a scalable biomanufacturing platform for the production of modified cells such as CAR-modified T-cells while eliminating on-target/off-tumor toxicity and decreasing the current production cost by 500 times (per treatment), and to attendant methods. The includes a first chamber for proliferat...