US Patent Issued to Mythic Therapeutics on July 7 for "pH-dependent antigen-binding constructs specific to FOLR 1" (Massachusetts Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,989, issued on July 7, was assigned to Mythic Therapeutics Inc. (Waltham, Mass.).

"pH-dependent antigen-binding constructs specific to FOLR 1" was invented by Alexander J. Nichols (Lincoln, Mass.), Brian P. Fiske (Cambridge, Mass.) and Nimish Gera (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are antigen-binding protein constructs capable of specifically binding FOLR1 or an epitope of FOLR1 presented on the surface of a target mammalian cell, wherein said antigen binding is pH-dependent. Provided are also uses of said antigen-binding protein constructs."

The patent was filed on June 5, 2020, under Application No. 17/...