US Patent Issued to ModernaTX on April 7 for "Assembly and error reduction of synthetic genes from oligonucleotides" (Massachusetts Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,476, issued on April 7, was assigned to ModernaTX Inc. (Cambridge, Mass.).

"Assembly and error reduction of synthetic genes from oligonucleotides" was invented by Marcus R. Duvall (Cambridge, Mass.), Kevin Smith (Franklin, Mass.), Robin Huang (Norwood, Mass.) and Andrew Giessel (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a rapid, high-fidelity process to support synthesis of genes for in vitro transcription of modified messenger RNA. In this process, sequence errors resulting from amplification with oligonucleotides comprising inherent errors are significantly reduced."

The patent was filed on ...