ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,327, issued on March 17, was assigned to Merus B.V. (Utrecht, Netherlands).
"Mixed binding domains" was invented by Cornelis Adriaan De Kruif (Utrecht, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "A binding domain or a multimer or a variant thereof which comprises a variable region encoded by a nucleic acid based on, derived or obtained from an animal phylogenetically distal from a human, which variable region is paired with a human variable region."
The patent was filed on Dec. 27, 2019, under Application No. 17/417,291.
*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/nph-...