US Patent Issued to Merck Sharp & Dohme on Sept. 1 for "Processes for preparing conjugates of the IL-2 protein" (New Jersey Inventors)

ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,723,058, issued on Sept. 1, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Processes for preparing conjugates of the IL-2 protein" was invented by Joshua Lee (Parlin, N.J.), Gregory F. Pirrone (Springfield, N.J.), Michael J. Iammarino (Manalapan, N.J.) and David J. Roush (Colts Neck, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are novel processes for preparing IL-2 conjugates with one or more water-soluble polymers. In one embodiment, the IL-2 conjugate comprises five poly(ethylene glycol) polymers each of which is covalently attached to the IL-2 moiety via a releasable linkage to an amino group of the IL-2 moiety."

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