US Patent Issued to Merck Sharp & Dohme on Oct. 6 for "Spirotricycle RIPK1 inhibitors and methods of uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,190, issued on Oct. 6, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Spirotricycle RIPK1 inhibitors and methods of uses thereof" was invented by Abdelghani Abe Achab (Melrose, Mass.), Jenny Lorena Rico Duque (Canton, Mass.), Xavier Fradera (Boston), Joey L. Methot (Westwood, Mass.), Phieng Siliphaivanh (Newton, Mass.), Brandon A Vara (Boston) and Hongjun Zhang (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are compounds of Formula I; and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, m, n, and p are as defined herein. The compounds of Formula I, and pharmaceutically acceptable salts thereof, act a...