ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,690, issued on July 21, was assigned to Merck Sharp & Dohme LLC (Rahway, N.J.).

"Macrocyclic urea orexin receptor agonists" was invented by Kira A. Armacost (Doylestown, Pa.), Maria Irina Chiriac (Hatfield, Pa.), Danielle M. Hurzy (Garnet Valley, Pa.), Jeffrey C. Kern (Gilbertsville, Pa.), Jian Liu (Edison, N.J.), Peter J. Manley (Harleysville, Pa.), Vanessa L. Rada (Glenside, Pa.), Michael T. Rudd (Collegeville, Pa.), Craig A. Stump (Pottstown, Pa.), Zhe Wu (Blue Bell, Pa.) and Dong Xiao (Warren, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to macrocyclic urea compounds which are agonists of orexin receptors...