ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,791, issued on July 21, was assigned to MEMORIAL SLOAN-KETTERING CANCER CENTER (New York).
"Free PSA antibodies as diagnostics, prognostics and therapeutics for prostate cancer" was invented by Charles L. Sawyers (New York), David Ulmert (Brooklyn, N.Y.), Jason Lewis (New York), Michael J. Evans (New York) and Hans Lija (New York).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods of monitoring and measuring tumor-associated free PSA ("fPSA") with antibody polypeptides as an indication of androgen receptor signaling. In a particular embodiment, the methods may be used to assess the efficacy of anti-androgen and/or g...