ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,694, issued on May 26, was assigned to Medizinische Hochschule Hannover (Hannover, Germany).
"All-in one vector for CAR and therapeutic effector molecule" was invented by Axel Schambach (Hannover, Germany), Katharina Zimmermann (Hannover, Germany), Hinrich Abken (Geiselhoring, Germany) and Johannes Kuhle (Cologne, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "Immune cells containing a nucleic acid construct, also referred to as a vector or viral vector, for use in immune therapy, e.g. for use in the treatment of cancer, or for use in the treatment of autoimmune disease, or for use in the treatment of GvH or HvG. The nucleic acid construct co...