ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,773,437, issued on Oct. 27, was assigned to Mayo Foundation for Medical Education and Research (Rochester, Minn.).

"Oncolytic viruses and methods for using oncolytic viruses" was invented by Laura Evgin (Rochester, Minn.), Richard G. Vile (Rochester, Minn.), Amanda L Huff (Rochester, Minn.) and Timothy J. Kottke (Oronoco, Minn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This document relates to methods and materials for treating cancer. For example, engineered viruses (e.g., oncolytic viruses) encoding one or more inhibitors of apolipoprotein B editing complex 3B (APOBEC3B) polypeptide activity or expression and methods for using such viruses as an ...