ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,784,872, issued on Nov. 3, was assigned to MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (Berlin).

"Method for engineering synthetic cis-regulatory DNA" was invented by Gaetano Gargiulo (Berlin).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to methods for generating cell-type specific expression cassettes and reporter vectors, as well as nucleic acid constructs that can be generated by such methods. The cell-type specific expression cassettes and reporter vectors are characterized synthetic cis-regulatory DNA, also termed synthetic locus regions (sLCRs). sLCRs allow for a cell-type specific expression of ...