US Patent Issued to MannKind on July 14 for "Microcrystalline diketopiperazine compositions and methods" (Connecticut, New York Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,811, issued on July 14, was assigned to MannKind Corp. (Danbury, Conn.).

"Microcrystalline diketopiperazine compositions and methods" was invented by Bryan R. Wilson (Brewster, N.Y.), Joseph J. Guarneri (Stamford, Conn.) and Marshall L. Grant (Newtown, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are DKP microcrystals made by an improved method where they do not irreversibly self-assemble into microparticles. The microcrystals can be dispersed by atomization and re-formed by spray drying into particles having spherical shell morphology. Active agents and excipients can be incorporated into the particles by spray drying a sol...