US Patent Issued to MAB DISCOVERY on March 3 for "Agonistic CD40 antibodies" (German Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,533, issued on March 3, was assigned to MAB DISCOVERY GMBH (Neuried, Germany).

"Agonistic CD40 antibodies" was invented by Stephan Fischer (Weilheim, Germany) and Karsten Beckmann (Vaterstetten, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to humanized monoclonal antibodies or antigen-binding fragments thereof that specifically bind to human CD40 receptor and induce CD40 signaling independent of FcGamma mediated CD40 receptor crosslinking. The antibodies of the present invention bind to a CD40 epitope that overlaps with the epitope of the CD40 ligand can activate human APCs. The present invention also provides...