US Patent Issued to Lyell Immunopharma on July 14 for "NR4A-deficient cells expressing c-Jun and uses thereof" (California Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,879, issued on July 14, was assigned to Lyell Immunopharma Inc. (South San Francisco, Calif.).

"NR4A-deficient cells expressing c-Jun and uses thereof" was invented by Viola Lam (South San Francisco, Calif.) and Rachel Christina Lynn (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of promoting a persistent effector function of immune cells, comprising modifying the cells to overexpress c-Jun and reduced levels of a NR4A gene and/or protein. Also provided are modified cells, e.g., immune cell, which have been modified to overexpress c-Jun and express reduced levels of NR4A gene and/o...