ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,104, issued on Sept. 8, was assigned to LUNELLA BIOTECH INC. (Ontario, Canada).
"Therapeutic methods for preventing tumor metastasis and tumor recurrence" was invented by Michael P. Lisanti (Didsbury Village, Great Britain) and Federica Sotgia (Didsbury Village, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "Cancer stem cells are responsible for tumor recurrence, distant metastasis and drug-resistance, in the vast majority of cancer patients. There exists an urgent need to identify new mitochondrial inhibitor drugs that can target and eradicate CSCs, and companion diagnostics to identify candidates for mitochondrial inhibition therapy....