ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,787, issued on July 21, was assigned to Lipovectra Inc. (San Antonio).

"Lipid nanoparticles with RNA for cosmetic treatment" was invented by Frank Ho Pak Lau (River Ridge, La.) and Jason Bourgeois (San Antonio).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for directing a change in cell state of white adipose tissue (WAT) which involve treating WAT cells with mRNA encapsulated inside lipid nanoparticles (LNPs). The mRNA encodes UCP1 or other proteins that may transition WAT to brown adipose tissue (BAT). The LNP may contain (C14-4:NCL:Cholesterol:PEG/Lipid Conjugate) at the molar ratio of (35:16:46.5:2.5), (50:10:38.5:1.5) or (56.5:10:31.8:...