ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,752,107, issued on Oct. 6, was assigned to LEONHARDT VENTURES LLC (Mission Viejo, Calif.).
"Modulation of SIRT" was invented by Howard J. Leonhardt (Mission Viejo, Calif.) and Jorge Genovese (Irvine, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described is a low voltage, pulsed electrical stimulation device for modulating the expression of sirtuin ("SIRT"), a useful protein, by tissues. Also described are methods of enhancing expression of SIRT in cells, particularly a method of stimulating the expression and/or release of SIRT in a cell having a gene encoding SIRT, wherein the method includes applying a bioelectric signal of, within 15%, 50 Mu...