US Patent Issued to Leadartis on Feb. 17 for "Single chain fusionconstructs comprising multimeric antibody fragments fused to collagen trimerization domains" (Spanish Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,867, issued on Feb. 17, was assigned to Leadartis S.L. (Madrid).

"Single chain fusionconstructs comprising multimeric antibody fragments fused to collagen trimerization domains" was invented by Luis Alvarez Vallina (Madrid) and Laura Sanz Alcober (Madrid).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the field of biomedicine and antibody engineering. Specifically, it relates to mono and multispecific multivalent single chain polypeptide molecules and derivatives thereof, preferably to multispecific single chain (tandem) trimerbodies with defined stoichiometry, to nucleic acid sequences and vectors encoding thereof, a...