ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,662, issued on July 21, was assigned to Lanzhou Chemspec Technology Co. Ltd. (Lanzhou, China) and Shanghai Chemspec Corp. (Shanghai).
"Use of silicon compounds in cyclization reactions" was invented by Li He (Shanghai), Xiaoliang Li (Shanghai), Zhenli Liu (Shanghai), Zhong Tian (Shanghai) and Hanqing Duan (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "A first aspect of the present invention provides a method for the preparation of 2-chloro-5-chloromethylpyridine, comprising: performing a cyclization reaction on 4,5-dichloro-4-methoxypentanenitrile in presence of a silicon compound and an acylamide compound to obtain 2-chloro-5-chloromethyl...