US Patent Issued to KYOTO UNIVERSITY on July 7 for "Method of producing a mesodermal-lineage primitive streak cell" (Japanese Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,144, issued on July 7, was assigned to KYOTO UNIVERSITY (Kyoto, Japan).

"Method of producing a mesodermal-lineage primitive streak cell" was invented by Shinichi Sueta (Kyoto, Japan), Tomoko Kasahara (Kyoto, Japan) and Kenji Osafune (Kyoto, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of producing a mesodermal-lineage primitive streak cell includes a first step of culturing pluripotent stem cells in a medium containing FGF2, BMP (bone morphogenetic protein) 4, a GSK-3Beta inhibitor, and retinoic acid or a derivative thereof and a second step of culturing cells obtained in the first step in a medium containing FGF2, a GSK-3Beta inhibi...