ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,381, issued on March 3, was assigned to KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands).

"Systems and methods for contrast enhanced imaging" was invented by Shiying Wang (Melrose, Mass.), Thanasis Loupas (Bothell, Wash.), Jeffry Earl Powers (Bainbridge Island, Wash.), Claudia Errico (Cambridge, Mass.), William Tao Shi (Wakefield, Mass.), Paul Sheeran (Woodinville, Wash.) and Charles Tremblay-Darveau (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Systems and methods for visualizing microbubbles for contrast-enhanced imaging are described herein. Microbubbles may be visualized by multi-pixel spots by identifying and localizing individual mi...