ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,926, issued on July 7, was assigned to Kobenhavns Universitet (Copenhagen K, Denmark) and Rigshospitalet (Copenhagen O, Denmark).
"Tetrazine compounds for in vivo imaging" was invented by Andreas Kjaer (Frederiksberg, Denmark), Ida Nymann Petersen (Copenhagen O, Denmark), Matthias Manfred Herth (Malmo, Sweden) and Jesper Langgard Kristensen (Copenhagen N, Denmark).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to novel tetrazine compounds of formula I, wherein one of R1-R5 is 18F, for use in pretargeted in vivo imaging. The compounds are suitable for use in click chemistry, i.e. reactions that join a targeting molecule an...