US Patent Issued to Keygene on Aug. 4 for "Genotyping of polyploids" (Dutch Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,522, issued on Aug. 4, was assigned to Keygene N.V. (Wageningen, Netherlands).

"Genotyping of polyploids" was invented by Stefan John White (Wageningen, Netherlands) and Rene Cornelis Josephus Hogers (Wageningen, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "The current invention pertains to a reliable method for determining the relative frequency of a sequence variant of interest in a nucleic acid sample derived from at least one polyploid cell, wherein the method uses a UMI to correct for any amplification biases. The invention further pertains to the use of a UMI for accurately determining the relative frequency of a sequence variant ...