US Patent Issued to KEAISE MEDICINE WUHAN on Aug. 4 for "Aryl-fused isoselenazole compound containing tetrazine substituent, synthesis method therefor, and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,287, issued on Aug. 4, was assigned to KEAISE MEDICINE WUHAN CORP. (Wuhan, China).

"Aryl-fused isoselenazole compound containing tetrazine substituent, synthesis method therefor, and use thereof" was invented by Huihui Zeng (Wuhan, China), Wenxuan Jiao (Wuhan, China) and Hanwei Yin (Wuhan, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "An aryl-fused isoselenazole compound contains a tetrazine substituent represented by formulas (I) and/or (II). The compound has an inhibitory activity on TrxR, and has the feature of targeting the TrxR target. Therefore, the compound has a good antitumor effect on tumors, particularly, gliomas. It effectively inh...