US Patent Issued to Karyopharm Therapeutics on July 7 for "Methods of synthesis of heteroaryl derivatives of triazolyl acrylamides and crystalline forms" (Canadian, American Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,939, issued on July 7, was assigned to Karyopharm Therapeutics Inc. (Newton, Mass.).

"Methods of synthesis of heteroaryl derivatives of triazolyl acrylamides and crystalline forms" was invented by Erkan Baloglu (Stoneham, Mass.), Brian C. Austad (Tewksbury, Mass.), David G. Roe (Rockwood, Canada), Andrew Leduc (Wilmington, Mass.), Stephen Edmund Gottschling (N. Aurora, Canada) and Evan Hecker (Arlington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method of preparing a compound represented by structural formula (VII), comprising reacting a compound represented by structural formula (II), with a compound rep...