ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,390, issued on Oct. 6, was assigned to KANEKA Corp. (Osaka, Japan).
"Method for producing cell sheet" was invented by Fumie Ikebuchi (Kobe, Japan), Tomoyuki Nakaishi (Kobe, Japan) and Fumiko Hara (Kobe, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method for preparing a cell sheet having a durable strength in practical use with good reproducibility within a period of time as short as possible, regardless of a culture medium additive or a type of culture vessel to be used is provided. The method for producing a cell sheet comprises a step of culturing mesenchymal stem cells in a medium containing an ascorbic acid species at 0.3 mM or higher ...