US Patent Issued to Kaken Pharmaceutical, Brickell Biotech on Aug. 11 for "Crystalline form of sofpironium bromide and preparation method thereof" (Japanese, American Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,682, issued on Aug. 11, was assigned to Kaken Pharmaceutical Co. Ltd. (Tokyo) and Brickell Biotech Inc. (Boulder, Colo.).

"Crystalline form of sofpironium bromide and preparation method thereof" was invented by Kazuyoshi Marubayashi (Shizuoka, Japan), Masahito Watanabe (Shizuoka, Japan) and Herbert R. Brinkman (Fort Collins, Colo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A cocrystal containing the 1'R-diastereomer and the 1'S-diastereomer of sofpironium bromide at a ratio of 1:3 (Form CO), a crystal mixture (for example, Form B) containing Form CO and a crystalline form of the 1'R-diastereomer (Form MN), and a method for preparing sofpironium ...