ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,080, issued on July 14, was assigned to JSR Corp. (Tokyo) and KEIO UNIVERSITY (Tokyo).

"Proliferative liver organoid, metabolically activated liver organoid, and use thereof" was invented by Norio Masuda (Tokyo), Toshiro Sato (Tokyo) and Ryo Igarashi (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A production method for a proliferative liver organoid includes culturing liver stem cells or a tissue fragment including liver stem cells in a growth medium to obtain a proliferative liver organoid, in which the growth medium contains an interleukin-6 family cytokine. A production method for a metabolically activated liver organoid includes culturin...