ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,778,989, issued on Nov. 3, was assigned to Jiangsu Target Biomedical Research Institute Co. Ltd. (Changzhou, China).
"Efficient traceless gene editing system for Salmonella and use thereof" was invented by Zichun Hua (Changzhou, China), Jiahuang Li (Changzhou, China), Chao Han (Changzhou, China), Menghui Wang (Changzhou, China), Junjie Zhou (Changzhou, China) and Jing Li (Changzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "An efficient and scarless gene editing system for Salmonella and the use thereof are provided. LambdaRed recombinase is used to promote a double crossover of a DNA template with a genomic target site, the CRISPR/Cas9 system...