US Patent Issued to Jiangnan University on June 9 for "P450 cytochrome enzyme for andrographolide synthesis and its application" (Chinese Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,936, issued on June 9, was assigned to Jiangnan University (Wuxi, China).

"P450 cytochrome enzyme for andrographolide synthesis and its application" was invented by Jingwen Zhou (Wuxi, China), Shan Li (Wuxi, China), Song Gao (Wuxi, China), Sha Xu (Wuxi, China), Weizhu Zeng (Wuxi, China) and Shiqin Yu (Wuxi, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a P450 cytochrome enzyme for andrographolide synthesis and its application, belonging to the field of bioengineering. The present disclosure uses Saccharomyces cerevisiae CEN.PK2-1D as a host, and implements knockout of ROX1 and GAL80 genes on the genome, and inte...