ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,931, issued on June 2, was assigned to Janssen Biotech Inc. (Horsham, Pa.).

"CALR and JAK2 T-cell receptors" was invented by Rebecca Hanson (Harleysville, Pa.), Vinod Krishna (Philadelphia), Manuel Alejandro Sepulveda (West Windsor, N.J.) and Patrick Wilkinson (Collegeville, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are T-cell receptors (TCRs) that bind to CALR or JAK2 antigens. Also described are T-cell receptors (TCRs), polynucleotides, vectors that encode the TCRs, and cells comprising the TCRs, and methods of treatment."

The patent was filed on April 4, 2022, under Application No. 17/712,661.

*For further information, ...