US Patent Issued to Janssen BioPharma on June 9 for "Synthesis of oligonucleotides and related compounds" (California Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,761, issued on June 9, was assigned to Janssen BioPharma Inc. (San Francisco).

"Synthesis of oligonucleotides and related compounds" was invented by Minghong Zhong (San Bruno, Calif.), Yi Jin (Carlsbad, Calif.), Dinesh Gala (Monroe, Calif.) and Marija Prhavc (Encinitas, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of synthesizing oligonucleotides via new intermediates on a cleavable support having an azidomethyl moiety are disclosed. The method comprises multiple reaction cycles, each of which comprises sequential coupling a nucleoside or oligonucleotide subunit on a cleavable support having an azidomethyl moiety and a nucleoside pho...