US Patent Issued to IPROGEN BIOTECH on June 2 for "Antibody-payload conjugates with enhanced delivery domain and uses thereof" (Canadian Inventors)

ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,944, issued on June 2, was assigned to IPROGEN BIOTECH INC. (Burnaby, Canada).

"Antibody-payload conjugates with enhanced delivery domain and uses thereof" was invented by Keun Ho Lee (Coquitlam, Canada), Leo Yen-Cheng Lin (Surrey, Canada), Ranjani Vaidyanathan (Vancouver, Canada) and Paula Lario (Vancouver, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a covalent conjugate. The conjugate includes an antibody or antibody derivative, at least two LL37-derived polypeptides, and a payload. The antibody or antibody derivative targets a cell that has phosphatidylserine in its outer leaflet. The payload includes: a sm...