ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,358, issued on May 12, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).
"Compounds and methods for reducing PLN expression" was invented by Dieter A. Kubli (Santee, Calif.), Brooke A. Anderson (San Diego), Adam Mullick (Carlsbad, Calif.) and Eric E. Swayze (Encinitas, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are oligomeric compounds, methods, and pharmaceutical compositions for reducing the amount or activity of PLN RNA in a cell or animal, and in certain instances reducing the amount of phospholamban protein in a cell or animal. Such oligomeric compounds, methods, and pharmaceutical compositions are useful to trea...