US Patent Issued to Ionis Pharmaceuticals on April 7 for "Modulation of prekallikrein (PKK) expression" (California Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,485, issued on April 7, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Modulation of prekallikrein (PKK) expression" was invented by Susan M. Freier (San Diego) and Huynh-Hoa Bui (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate PKK-associated diseases, disorders, and conditions."

The patent was filed on Oct. 18, 2023, under Application No. 18/489,316.

*For further information, including images, charts and tables, please visit: http://patf...