US Patent Issued to Ionis Pharmaceuticals on April 14 for "Compositions for modulating C9ORF72 expression" (California Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,970, issued on April 14, was assigned to Ionis Pharmaceuticals Inc. (Carlsbad, Calif.).

"Compositions for modulating C9ORF72 expression" was invented by C. Frank Bennett (Carlsbad, Calif.), Susan M. Freier (San Diego), Frank Rigo (Carlsbad, Calif.) and Eric E. Swayze (Encinitas, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods for reducing expression of C9ORF72 mRNA and protein in an animal with C9ORF72 specific inhibitors. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C9ORF72 specific inhibitors include antisense compound...